LPS induces rapid IL-10 release by M-CSF-conditioned tolerogenic dendritic cell precursors
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چکیده
منابع مشابه
TGF-beta combined with M-CSF and IL-4 induces generation of immune inhibitory cord blood dendritic cells capable of enhancing cytokine-induced ex vivo expansion of myeloid progenitors.
Tolerogenic dendritic cells (DCs) may be valuable in transplantation for silencing immune reaction. Macrophage colony-stimulating factor (M-CSF)/IL-4 induces differentiation of cord blood (CB) monocytes into DCs (M-DCs) with tolerogenic phenotype/function. We assessed whether factors produced by tolerogenic DCs could modulate hematopoiesis. TGF-beta1 added to CB M-DC cultures induced bona fide ...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2007
ISSN: 0741-5400
DOI: 10.1189/jlb.0406267